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Isoniazid is used with other drugs to treat tuberculosisTBa serious infection that affects the lungs and sometimes other parts of the bodyIsoniazid is also used with other drugs to treat people with latentresting or nongrowingTB including those in close contact with people who have active TBa positive tuberculin skin testhuman immunodeficiency virusHIVand those with pulmonary fibrosisscarring of the lungs with an unknown causeIsoniazid is in a class of medications called antituberculosis agentsIt works by killing the bacteria that cause tuberculosis.

Frequency not reportedLupoid syndromesystemic lupus erythematosus-like syndromeRef]

Isoniazid is an antibioticIt prevents tuberculous bacteria from multiplying in the body.

Isoniazid may cause severe and sometimes fatal liver damageTell your doctor if you have or have ever had liver diseaseif you drink or have ever drunk large amounts of alcoholor if you are using or have ever abused injectable street drugsIf you experience any of the following symptomscall your doctor immediatelyexcessive tirednessweaknesslack of energyloss of appetitenauseavomitingdark yellow or brown urineyellowing of the skin or eyespain in the upper right part of the stomachor flu-like symptoms.

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for the treatment of tuberculosis in patients unable to take rifamycins or due to strains of mycobacterium tuberculosis resistant to the rifamycins, administer isoniazid once daily in combination with pyrazinamide, ethambutol, and a quinolone for 2 months, then isoniazid plus ethambutol and a quinolone for a treatment duration of 12 to 18 months.

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